Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE): In 2014, eHealth Africa was approached by the U.S. Centers for Disease Control and Prevention (CDC) to assist in the implementation of the first-ever clinical trial in Sierra Leone. The clinical trial was to test a vaccine against the Ebola Virus Disease. At the time Sierra Leone was facing a deadly Ebola outbreak.
United States Centers for Disease Control & Prevention
Sustained long-term facility for the STRIVE participant clinical trial records that meet mandated regulatory storage requirement.
In 2014, eHealth Africa was approached by the U.S. Centers for Disease Control and Prevention (CDC) to assist in the implementation of the first-ever clinical trial in Sierra Leone. The clinical trial was to test a vaccine against the Ebola Virus Disease. At the time Sierra Leone was facing a deadly Ebola outbreak.
In the end, STRIVE enrolled and vaccinated over 8,000 health care and front-line workers. 350+ Sierra Leonean clinicians were trained to enroll, vaccinate, and provide surveillance, also building a functioning cold chain to support -80 degree centigrade temperatures to keep the vaccine viable.
eHA facilitated the construction and maintenance of a climate controlled warehouse to maintain physical records of more than 8,000 participants of STRIVE. eHA’s ICT Technicians provided technical assistance to the Ministry of Health and Sanitation and College of Medicine and Allied Health Sciences (COMAHS).
eHA also works with Technical Resources International Inc (TRI) to maintain electronic clinical data.
eHA will continue to work with the COMAHS to prepare for a United States Federal Drug Administration (FDA) audit of the participants, as required for licensure of the Ebola Vaccine used in STRIVE.
The intended outcome is sustained long-term storage facility for the STRIVE participants clinical trial.
eHA’s role is to complete regulatory requirements for the storage of participant data mandated for clinical trials. Here are some of the innovations eHealth Africa facilitated for the STRIVE program:
Provide logistics and technical support to the Long Term Storage.
A mobile electronic participant registration system.
A toll-free line hosted by a 24-hour call center for participants enrolled in the trial.
Operations and logistics support to the seven enrollment and vaccination sites.
Renovation of the enrollment and vaccination sites prior to opening.
Contract creation with hospitals around the country to provide free medical care to 8000+ enrolled participants for the duration of the trial.
Government of Sierra Leone
Wide Global Public
health care workers and frontline workers were vaccinated against Ebola Virus Disease in Western Area, Port Loko, Bombali and Tonkolili Districts.